Type 1 diabetes, once known as insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin. Insulin is a hormone needed to allow sugar (glucose) to enter cells to produce energy.

Different factors, including genetics and some viruses, may contribute to type 1 diabetes. Although type 1 diabetes usually appears during childhood or adolescence, it can develop in adults.

Despite active research, type 1 diabetes has no cure. Treatment focuses on managing blood sugar levels with insulin, diet and lifestyle to prevent complications.

What are the symptoms?

Type 1 diabetes signs and symptoms can appear relatively suddenly and may include:

• Increased thirst
• Frequent urination
• Bed-wetting in children who previously didn’t wet the bed during the night
• Extreme hunger
• Unintended weight loss
• Irritability and other mood changes
• Fatigue and weakness
• Blurred vision

What are possible causes?

The exact cause of type 1 diabetes is unknown. Usually, the body’s own immune system — which normally fights harmful bacteria and viruses — mistakenly destroys the insulin-producing (islet, or islets of Langerhans) cells in the pancreas. Other possible causes include:

• Genetics
• Exposure to viruses and other environmental factors

Risk factors

Some known risk factors for type 1 diabetes include:

• Family history.Anyone with a parent or sibling with type 1 diabetes has a slightly increased risk of developing the condition.
• The presence of certain genes indicates an increased risk of developing type 1 diabetes.
• The incidence of type 1 diabetes tends to increase as you travel away from the equator.
• Although type 1 diabetes can appear at any age, it appears at two noticeable peaks. The first peak occurs in children between 4 and 7 years old, and the second is in children between 10 and 14 years old.

What are the treatments for diabetes?

Treatments for diabetes depend on the type. Common treatments include a diabetic meal plan, regular physical activity, and medicines. Some less common treatments are weight loss surgery for either type and an artificial pancreas or pancreatic islet transplantation for some people with type 1 diabetes.

What are the types of medicines for type 1 diabetes?

If you have type 1 diabetes, you must take insulin because your body no longer makes it. Different types of insulin start to work at different speeds, and the effects of each last a different length of time. You may need to use more than one type.

You can take insulin several different ways. The most common are with a needle and syringe, an insulin pen, or an insulin pump. If you use a needle and syringe or a pen, you have to take insulin several times during the day, including with meals. An insulin pump gives you small, steady doses throughout the day. Less common ways to take insulin include Inhalers, injection ports, and jet injectors.

In rare cases, taking insulin alone might not be enough to manage your blood sugar. Then you would need to take another diabetes medicine.